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CSEC>> Biology

Meiosis
Joanna George-Johnson, Contributor

Last time, we spoke of a type of cell division that maintained the chromosome number at the end of the process. This week, we will look at a next type of cell division. However, this cell division will decrease the number of chromosomes by half, that is, Haploid cells are made.

Meiosis is the process by which gametes (sperm/egg/pollen) are made. Therefore, this process only occurs in organisms that carry out sexual reproduction.

In human females, the production of eggs occurs before they are born. However, at birth they are immature. At puberty, the eggs mature, one each month. In males, the production of sperms starts at the onset of puberty. (More of this will be discussed when reproduction is covered.)

  • Meiosis is a process of cell division which results in the production of four daughter cells from a single-parent cell. The daughter cells are not identical to one another or to the original parent cell. Meiosis is a process to convert a diploid cell to a haploid gamete, and cause a change in the genetic information to increase diversity in the offspring.

The rationale for meiosis

  • Formation of new individual happens by a combination of two haploid sex cells (gametes).

  • Fertilisation: This is a combination of genetic information from two separate cells that have one half the original genetic information.

  • Gametes for fertilisation usually come from separate parents.

  • If both gametes are haploid (n), then the individual that is formed will have the full complement of chromosomes (2n).

Meiosis is a very complex process so for simplicity the process is normally studied in two stages with four phases each. This is an area where students tend to get confused especially with keeping the number of chromosomes straight. I will attempt to give clarity. So in an effort to diffuse the confusion I will use a table to describe the process.

STAGEPHASEDESCRIPTION# Chromosomes (humans)# Chromatids' (humans)
Prophase I Already duplicated Homologous² chromosomes pair and stands cross over. Forming chiasmata. Chromosomes condense thus can be viewed with microscope. Nucleus starts to disappear4692
Metaphase I Homologus chromosomes align at the equator of cell. The alignment is random, with either parental homologue on a side.4692
Anaphase I The crossed over sections separate. Chromosomes, each with two chtomatids, move to opposite side of cell46 (23 on either side)92 (46 on either side)
Telophase I Nuclear envelopes from around each set of chromosomes. Forming two cells. In preparation for Meiosis II23 in each if the two cells46 in each of the two cells
Prophase II

The chromosomes in each cell shorten and become visible under the microscope.

The nuclear envelope disappears

23 in each of the two cells46 in each of the two cells
Metaphase II The chromosomes (still connected by a centromere) line up on the middle of the cell. Spindle fibres emanating from the centrioles connect to the centromeres from either side.23 in each of the two cells46 in each of the two cells

1. Cromatids: Strands of newly-duplicated chromosome still joined together. Therefore, 1 duplicated chromosome = 2 cromatids.

2. Homologous chromosome: Two chromosomes of the same type. (one from your mom and the other from your dad). For example, a pair of chromosome 'number 6' in the same cell is called homologous.

 Anaphase IIThe centromeres that join the sister chromatids split. The sister chromatids separate. They move to opposite sides of the cell until they have separated into two groups near the poles of the spindle.23 in each of the two cells

46 in each of the two cells

Not called chromatids by late anaphase called chromosomes instead.

 Telophase IIIn telophase, the chromosomes, which were distinct and condensed, begin to disperse and become less visible under the microscope. A nuclear envelope re-forms around each cluster of chromosomes. The spindle begins to break apart, and a nucleolus becomes visible in each daughter nucleus.23 in each of the four cellsnot called chromatids anymore
     

Questions

1. A human cell has 46 total or 23 pairs of chromosomes. Following mitosis, the daughter cells would each have a total of ______ chromosomes. After meiosis I, the two daughter cells would have _____chromosomes, and after meiosis II ______ chromosomes.

2. The process of meiosis produces four cells with non-identical chromosomes. At what stage does this diversification takes place?

3. Which stage of meiosis do cells become haploid?

Joanna George-Johnson teaches at Ardenne High School.
Email: Masterbio@gmail.com.

 
 
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